WHO advises against the use of remdesivir in patients admitted for Covid-19

Health has registered 6,915 new cases of coronavirus in the last 24 hours and 252 deaths. Some alarming data but that improves a little compared to the last days. The Community of Madrid continues to be the protagonist due to its effective management of the crisis that is causing the Government to retreat. The last thing: Fernando Simón says that antigen tests in pharmacies can help when he has been criticizing him since Ayuso proposed it.

WHO advises against the use of remdesivir in patients admitted for Covid-19

The Guidelines Development Group of the World Health Organization (WHO) has issued a report, published in the journal ‘The BMJ’, in which it advises against the use of remdesivir in patients admitted for Covid-19, since there is no evidence that it improves survival or reduces the need for ventilation.

Remdesivir has been used around the world as a potentially effective treatment for severe Covid-19 and is increasingly being used to treat patients admitted to hospitals, although its role in clinical practice remains ‘uncertain’.

Faced with this scenario, the WHO has carried out a new review of the scientific evidence available to date in which the effects of various pharmacological treatments in the approach to Covid-19 are compared. In fact, it includes data from four international randomized trials involving more than 7,000 patients hospitalized for COVID-19.

After extensively reviewing this evidence, the WHO international expert panel, which includes four patients who have had Covid-19, has concluded that remdesivir does not have a significant effect on mortality or other important patient outcomes such as , for example, the need for mechanical ventilation or clinical improvement.

“The scientific evidence is low and does not prove that it has any benefit in patients,” the experts have pointed out, although they support conducting trials evaluating remdesivir in order to increase the scientific evidence in this regard.

Simón warns that antigen tests can be useful if they are done correctly

The director of the Center for the Coordination of Health Alerts and Emergencies, Fernando Simón, has warned that the antigen test can be useful if it is done correctly, remembering that they cannot detect past infections.

At a press conference, and before the debate on the performance of these tests in pharmacy offices, Simón recalled that currently there is a risk of reinfection by coronavirus, a fact that perhaps these tests do not detect accurately.

“There are many ways to use them, but the problem is when these tests, or other tests, are used for what they are not made. Therefore, if they are done well and interpreted correctly, all that remains is to look carefully at where, when and for what purpose they are doing it, ”explained Simón.

That said, the director of the Center for Coordination of Health Alerts and Emergencies has referred to the study carried out by researchers from the La Jolla Institute for Immunology (United States) in which it is pointed out that immunity against Covid-19 can last, at least , eight months and could extend years, noting that “everything seems to indicate” that it can last “much longer” than hitherto believed.

Health registers 16,233 new cases of Covid-19, 6,915 in the last 24 hours

The autonomous communities have notified the Ministry of Health this Thursday 16,233 cases of Covid-19, of which 6,915 have been diagnosed in the last 24 hours, compared to the 7,090 registered on Wednesday, raising the global number of people infected by coronavirus to 1,541,574.

The current average rate of infections in Spain in the last 14 days is 436.27 cases per 100,000 inhabitants. “The incidence is decreasing, but they are still very high figures and are well above the objectives we have set, the ideal being below 60 cases per 100,000 inhabitants,” said the director of the Center at a press conference Coordination of Health Alerts and Emergencies, Fernando Simón.

As for those killed by Covid-19, the department headed by Salvador Illa has notified 252 more this Thursday, 1,313 in the last week. This brings the global death toll from coronavirus in Spain to 42,291 people.

There are currently 18,961 patients admitted for Covid-19 throughout Spain and 3,125 in an ICU, although in the last 24 hours there have been 1,727 admissions and 2,246 discharges. In addition, in the last week 4,243 people have been admitted to a hospital as a result of the infection caused by the contagion of the coronavirus and 340 in an ICU.

The occupancy rate of beds occupied by coronavirus currently stands at 15.18 percent and in ICUs at 31.66 percent. “We remain in a very slight decrease in ICU income,” said Simón.

Of the 6,915 people diagnosed with Covid-19 in the last day, 1,312 have been located in Madrid, although 490 in Andalusia, 531 in Aragon, 455 in Asturias, 84 in the Balearic Islands, 115 in the Canary Islands, 235 in Cantabria, 146 in Castilla -La Mancha, 33 in Castilla y León, 959 in Catalonia, 42 in Ceuta, 248 in the Valencian Community, 216 in Extremadura, 630 in Galicia, 33 in Melilla, 200 in Murcia, 138 in Navarra, 922 in the Basque Country and 126 in The Rioja.

Regarding deaths, Health has already registered 3,472 deaths in Andalusia (227 in the last week); in Aragon 2,129 (180 in the last seven days); in Asturias 775 (128 in the last week); in the Balearic Islands 398 (nine in the last seven days); in the Canary Islands 321 (10 in a week); in Cantabria 292 (14 in the last seven days); in Castilla-La Mancha 3,635 (66 in the last week); and in Castilla y León 4,253 (168 in the last seven days).

In addition, 7,450 people have died in Catalonia as a result of the coronavirus (36 in the last seven days); In Ceuta, 45 deaths have been recorded since the beginning of the pandemic (three in the last week); in the Valencian Community 2,124 (106 in the last seven days); in Extremadura 872 (45 in one week); in Galicia 1,114 (68 in the last seven days); in Madrid 11,181 (96 in the last seven days); in Melilla 35 (four in the last seven days); in Murcia 521 (45 in the last seven days); 817 in Navarra (33 in the last seven days); 2,334 in the Basque Country (57 in the last seven days); and in La Rioja 523 (18 in the last seven days).

Regarding diagnostic tests, from November 9 to November 15, 1,111,297 have been performed, of which 787,571 were PCR and 323,726 antigen tests. The total positivity rate stands at 12.12 percent.

“Maintaining a very high diagnostic capacity, positivity continues to decline, so we are close to our maximum detection capacity because the positivity index is maintained,” Simón emphasized.