Scientists model a map of how the brain looks after infection

A scientific investigation manages to model a map of the changes generated by the Coronavirus Covid-19 in infected patients.

One of the biggest uncertainties around Coronavirus Covid-19 is what happens to the human brain after suffering a contagion by SARS-CoV-2.

Although the disease attacks each individual differently, even registering few or no visible symptoms in most cases, it does manage to have an impact on the subjects’ organs.

Now a scientific investigation has emerged where it is finally possible to illustrate with greater precision how it affects the Covid-19 to the human brain.

Real impacts

The project has been developed by an international team of doctors from the United States and Canada, led by Dr. Geidy serrano from the Sun Health Research Institute in Arizona.

The preliminary results of his research have just been released for consultation and review at medRxiv. Although further development is lacking, these preliminary findings reveal that indeed a SARS-CoV-2 contagion can lead to acute neuropathology, leaving traces:

The findings of this study align with previously reported autopsy examinations in the brains of subjects with Covid-19.

Where it is found that serious complications such as encephalitis and large acute infarcts were present in relatively few subjects.

These results confirm the growing consensus that most of the neurological signs and symptoms associated with Covid-19 may be due to, not direct viral brain invasion.

But to systemic reactions such as coagulopathy, sepsis, autoimmune mechanisms or multiorgan failure.

To arrive at these findings, the researchers applied reverse transcriptase polymerase chain reaction (RT-PCR) assays.

While they exhaustively studied the presence of SARS-CoV-2 RNA in 16 brain regions of 20 people who had died from Covid-19.

With ages between 38 and 97 years of age, they found that most of the deceased presented typical neuropathological related to their age.

Only two people had a serious condition derived directly from their infection. One with a acute cerebral infarction and another with hemorrhagic encephalitis.

This would mean that a low percentage of cases would have symptoms that affect the brain. Although damage to other organs and systems could also impact, as they found in the autopsies.

Thanks to this, they achieved the mapping image shown above and the other photographs that help to observe how SARS-CoV-2 affects the human brain.