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COVID-19 : Coronavirus: AstraZeneca Vaccine vs Modern Vaccine: efficacy, dose, who gets vaccinated and how they are administered

The vaccine continues to be the great hope to end this pandemic that is affecting the entire planet, both at the health and socio-economic level. In Spain, for example, there are already different types of three laboratories that are being administered to a series of groups.

The vaccination plan aims to immunize as soon as possible the people who are in the age ranges of greatest risk, as well as groups that are on the front line in the fight against the disease.

The first to arrive in Spain was Pfizer / BioNTech, which has been administered since December 27, 2020. Then, two more have arrived, after the approval of the European Medicines Agency (EMA) of the European Union: that of Moderna and that of AstraZeneca. But what are the characteristics of each of these two?

Efficacy and necessary doses

Efficacy is the main difference between the two vaccines. Based on evidence from clinical trials, Moderna’s vaccine was shown to be 94.1% effective. This is a fairly high percentage, taking into account that the flu is around 60% -70%. For its part, that of AstraZeneca, according to the pharmacist itself, is 76% effective, although some recent studies place it at 63%.

The number of doses is two for both vaccines, but in each one the interval between the first dose and the second are different: 28 days have to pass in Moderna’s; while with AstraZeneca it can take up to 90 days on receiving the second booster dose.

It must be remembered that both would be prepared to be effective against british variant, although studies indicate that there is greater safety in the face of this variant in the AstraZeneca. Nevertheless, the latter would present more doubts when it came to the South African mutation, something that has caused his administration to be suspended in the African country.

Preservation of vaccines

Another feature that also differentiates these two drugs is the temperature at which they have to be stored. The one from the American laboratory should be stored at a temperature of -20ºC. Nevertheless, those from the UK can be kept at a much more acceptable temperature, between 2ºC and 8ºC.

Who can receive them?

According to the vaccination plan, defined this past Wednesday by the Public Health Committee of the National Health System, Moderna’s vaccine It will be administered according to age when the administrations in residences, health and dependents are finalized. Therefore, when these groups are finished vaccinating, vaccination will begin for those over 80 years of age; then to people who are between 70 and 79 years old; and later to those who are between 60 and 69 years old.

For its part, that of AstraZeneca in Spain will initially be administered to people who are between 45 and 55 years old. This decision comes, by the health authorities, after it was known that this vaccine could not be adapted, due to the lack of data on effectiveness and safety, for those over 55 years of age.