The Consortium for the Genomic Epidemiology of SARS-CoV-2 in Spain, SeqCOVID and the Higher Council for Scientific Research (CSIC) have carried out a report confirming the effectiveness of the March home confinement to reduce COVID-19 infections. Dated on October 26, this study shows how the main coronavirus genomes during the first wave of the pandemic in our country disappeared in mid-May.
This document has been produced based on the sequence of the coronavirus genome of 20,000 patients to try to understand how the virus reached Spain, as well as their transmission patterns.
SEC7 and SEC8 genotypes
The SEC7 and SEC8 genotypes were the main causes of the disease in our country. This is established by the report of the CSIC and SeqCOVID. These genomes caused the highest number of infections in Spain during the first months of the pandemic and correspond to the genotypes associated with the strains that arrived from China.
To carry out this study, the researchers analyzed the effect of confinement in Spain during the months of March and June, evaluating the growth of infections in the Spanish epidemic groups that registered more cases.
The experts analyzed the impact of confinement restrictions on the SEC7 and SEC8 genotypes. After that, they assure: “Confinement is highly effective with the disappearance of many of these successful genotypes.” That is why they affirm that Confinement was the key to success in eliminating the genotypes that were generating the most infections in the country.
A new confinement
In the last weeks, Some authorities in the country have considered a new home confinement to stop the second wave of infections. For that to happen, the Government should modify the state of alarm that collects the Royal Decree 926/2020, of October 25, by which it is declared the state of alarm to contain the spread of infections caused by SARS-CoV-2.
Knowing the data in this report, a new confinement could eliminate genotypes currently circulating in society Spanish and suppressing again the virus variants that cause more severe disease in those most vulnerable.